Mitral valve regurgitation, a condition where the blood flows backward instead of flowing forward is the most common heart valve disorder affecting over 2% of the general population globally, increasing with age. Mitral valve regurgitation [MR] occurs when the heart flaps do not close tightly. This leads to an alteration in the size and shape of the valve, which results in blood leak or backward flow of blood into the left atrium. A mitral valve disorder pushes the heart to pump that much harder, and can lead to atrial fibrillation or heart failure. If the disease causes severe symptoms, the doctor may recommend a procedure to replace or repair the dysfunctional valve. Minimally invasive technologies improving treatment access Open-heart surgery is the standard go-to treatment for MR. A contemporary survey in 877 patients shows that as many as a half of symptomatic patients presenting with severe MR could not undergo surgery because of high surgical risk factors such as old age, frailty, condition of the heart, kidney function, and comorbidities.